Search
Info
Warning
Danger

Study Resources (Chemistry)

  1.Why are the orange and red dyes typically smaller molecules than the blue dyes? Relate to the fundamental principles of color. 2.Drugs and dyes share at least two general similarities as a group of compounds. Discuss. Both classes of compounds include acids, bases, and neutrals and the basic compounds are nitrogenous.
0 Views
View Answer
1.Study Table 13.1, noting in particular the oxygen balance figures.  Predict which energetic is likely to be the largest component of propellant and explain your reasoning. Nitroglycerin, since it is the only material shown with a positive oxygen balance.  Note:  NG is the primary ingredient in most propellants, but other.
4 Views
View Answer
  10. The predator drug Rohypnol (flunitrazepam) when administered orally has a bioavailability (F) of 70%. A woman arrives unconscious in the emergency room with signs that a sexual assault may have occurred within the last hour. She weighs 120 lbs and a blood analysis reveals a Cp of this compound.
0 Views
View Answer
  12. The following data applies to the drug Rohypnol (flunitrazepam), FW 313.3: Log P pKa Structure t1/2 plasma t1/2 elimination Elimination 2.1 1.8 3 h 16–35 h 1% unchanged urine; 10% feces and the rest metabolites in urine Answer the following questions: a)Assuming a typical dose of 1 mg, what would be the expected concentration of unchanged drug in a urine sample of 25.
0 Views
View Answer
  3.Locate a reference that describes sample preparation in entomotoxicology. What approach is used to breakdown chitin? 4.From your knowledge of the structure of glucose and cellulose, identify which groups are infrared absorbers. Where in the spectrum would most IR spectral features be expected to appear?  Locate or obtain an IR spectrum.
0 Views
View Answer
  6. Calculate the oxygen balance for each of the 4 explosives in the previous question using the shortcut method (eq. 12.1).  Could any of these be used alone based on oxygen balance considerations only? a) PETN C5H8N4O12 b)Ethylene glycol dinitrate, EGDN C2H4N2O6 c)Triacetone triperoxide, TATP C9H18O6 d)Picric acid, C6H3N3O7   .
0 Views
View Answer
  5.Discuss the mechanism of color formation in the Walker test (Figure 13.16).  6.A commercial etching paste used for serial number restoration from copper consists of hydrochloric and nitric acids along with ferric chloride.  Assuming the redox reaction(s) are spontaneous, describe the likely mechanism of copper metal dissolution.   .
0 Views
View Answer
  7.  Using the balanced chemical equations obtained in the previous question, estimate Q value for each explosive on a per gram basis.  Use the following heats of formation ?H° values in kJ/mole. a) PETN: -520 b)EGDN: -227 c)TATP: -116 d)Picric acid: -245 8.  Using the balanced chemical equations obtained in question 5, calculate the.
0 Views
View Answer
1.Why is the term anhydroglucose used to describe glucose polymers? What classification of polymer does this place cellulose in? 2.Provide the chemical explanation for why lignin would be expected to contribute to the acidity of paper. What other groups are involved and how does the bound water in paper (Figure 15.17).
4 Views
View Answer
  10.Is SPME a destructive analysis?  Justify your answer. 11.Two common solvents used in clandestine drug labs are diethyl ether and acetone. Being less than vigilant in lab and safety practices, clandestine chemists often work with leaky equipment. If a person was brought to the emergency room under suspicious circumstances, where would.
0 Views
View Answer
  1.What is unusual about the formation of 7-aminoflunitrazepam based on what we discussed in Chapter 9? 2.Unknown to her, a woman is dosed with the typical anesthetic inducing dose of 50mg/kg of GHB.  She weighs 130 lbs.  If the half-life is taken as 0.7 hours, when will the concentration in her.
0 Views
View Answer
  3.Locate the structure of chlorophyll and categorize it. Might this substance be found in items of physical evidence? Suggest an analytical scheme to identify it. 4.An older resin system used in automotive paints exploited cellulosic-based resins such as nitrocellulose. What are the components of this resin system?  How does the.
0 Views
View Answer
  6.The propellant used in the solid rocket boosters during the Space Shuttle program were based on aluminum metal and ammonium perchlorate.  If these were the only two ingredients, what composition would produce a net zero oxygen balance? 7.Assume that the two main ingredients in a gunpowder formulation are nitrocellulose (NC) and.
0 Views
View Answer
  8.A death investigator returns from a scene of a questioned death.  The victim is an older woman with a history of depression.  The investigator found an empty prescription bottle for Valium (5 mg/tab) on the nightstand and a half-empty bottle of wine.  The investigator suspects the woman may have committed.
0 Views
View Answer
  11. Consider the following data regarding aspirin: pKa t1/2 plasma Principal metabolic reaction Conjugates with ~LD50 3.5 17 minutes hydrolysis Glucuronic acid 225 mg/kg Source: Galichet, L. Y., et al., ed., “Aspirin,” Clarke’s Analysis of Drugs and Poisons. London: Pharmaceutical Press, 2004, p. 652. Answer the following questions: a)What is the lethal dose for an adult female (130 lbs) reported in number of tablets.
0 Views
View Answer
  4.Based on the characteristics of cellulose, what group(s) of dyes would be appropriate for dying cotton and paper aside from those already discussed? Explain based on intermolecular forces such as ion-ion, ion-dipole, etc. 5.In 2002, Cargill Dow introduced a new synthetic fiber labeled PLA and made from lactic acid monomers. What.
0 Views
View Answer
  1.An older color-based presumptive test for saliva is based on the presence of the enzyme amylase. It employs starch gel and iodine in an interesting way. Explain how this test is performed, its chemical basis, and its limitations. How is this test related to material presented in this chapter? 2.Describe and.
0 Views
View Answer
  6.Could the cation exchange capacity of paper be used to characterize it?  Why or why not? What variables would have to be controlled? 7.A simple TLC experiment can be performed in which water-soluble inks are applied to filter paper and the chromatogram developed using water as the solvent. Explain what interactions.
1 Views
View Answer
1.Why is the term “blood concentration” not preferred for describing concentrations of drugs and metabolites in the bloodstream of living persons? 2.In normal urine, what form (protonated or not) would the following substances be in?     3.Show the net cell reaction for the fuel cell shown in Figure 10.17.   .
4 Views
View Answer
  6.An analyst prepares a homogenized liver sample by placing a weighed amount in a test tube, adding methanol, and sonicating.  The entire extract is placed on a SPE column, extracted, and dried.  She then reconstitutes the extract in a known volume of internal standard solution.  What is the problem with.
0 Views
View Answer
  4.The following data was reported for bullets and bullet fragments associated with the assassination of President John F. Kennedy in 1963 (for a complete list, see the reference below).  For the sake of this exercise, assume that 5 replicate analyses were used to generate the standard deviation.   ppm by weight, mean.
0 Views
View Answer