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Question : How does the inherent imprecision of recombination events during immunoglobulin

How does the inherent imprecision of recombination events during immunoglobulin gene rearrangement contribute to the diversity of the immune response?

Recombinational imprecision affects the number of various LV and J units that are included in the final mature chain.

Recombinational imprecision between any pair of LV and J regions provides variation in amino acid sequence during immunoglobulin formation.

Recombinational imprecision between any pair of LV and C regions provides variation in amino acid sequence during immunoglobulin formation.

Recombinational imprecision affects binding of methyl groups to the enhancer between the J and C regions, which initiates an immune response.

 

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