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41.Which of the following is a specific endogenous ligand for cannabinoid receptors?

a. noradrenalineb. anandamidec. serotonind. dopamine

42.Although amphetamine can provoke schizophrenia-like hallucinations with high doses, it is not typically classified as a hallucinogen because

a. its molecular structure is not like that of hallucinogenic drugs

b. it only has hallucinogenic properties in schizophrenics

c. it is not typically taken by humans for the purpose of provoking hallucinatory experiences

d. legal restrictions do not allow it to be classified as a hallucinogen

43.The most common treatment for a “bad trip” induced by LSD is

a. talking the person down through reassurance that the trip will subside soon

b. administration of an antipsychotic drug

c. administration of morphine

d. getting the person to vomit

44.When marijuana is administered orally,

a. its psychoactive effects are subjectively very similar to those that occur when it is smoked

b. it is considerably less potent than when it is when smoked

c. its metabolites can be detected in the urine for several weeks afterward

d. all of the above

45.Which of the following has recent research found to be reliably associated with marijuana use?

a. increased aggressive behaviorb. enlargement of the lateral ventricles of the brain

c. disruptions in short term memoryd. only b and c above

46.The major psychoactive compound in marijuana, delta-9-THC, has actions mediated by CB1 receptors. An endogenous ligand for this class of receptors is called

a. dopamineb. serotoninc. acetylcholined. anandamide

47.Which of the following is a common feature of typical monoamine-related hallucinogens?

a. rapid tolerance to their subjective effects

b. cross-tolerance to the effects of the drugs in this group

c. the absence of any notable abstinence symptoms upon cessation of use following chronic use

d. only a and b above

48.On which of the following pharmacological dimensions does cannabis (delta-9-THC) differ significantly from LSD, psilocybin and mescaline?

a. the degree to which they induce profound and intense perceptual distortions and hallucinatory experiences

b. their effects on wakefulness

c. the rate at which tolerance develops to their subjective effects

d. all of these

49.Which of the following effects of LSD in normal adults are similar to the symptoms commonly associated with schizophrenia?

a. profound, and typically pleasant, visual-perceptual distortions of the environment

b. enhanced empathy and concerns over interpersonal relationships

c. the psychotic state is highly responsive to suggestions from others

d. none of these

50.LSD, psilocybin and mescaline differ from each other primarily in terms of

a. their efficacy in inducing profound and intense perceptual distortions and hallucinatory experiences

b. their potency

c. ability to induce cross-tolerance to each other’s effects

d. their effects on autonomic nervous system activities

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