Test Bank for Hematology in Practice, 3rd Edition

Chapter 2. From Hematopoiesis to the Complete Blood Count Multiple Choice 1. What is the average M:E ratio for normal adult bone marrow? A. 1:3 B. 4:1 C. 1:4 D. 6:1 ANS: B OBJ: 2.6 2. The key organs involved in extramedullary hematopoiesis include the: A. Kidney and thymus B. Lymph nodes and heart C. Liver and spleen D. Kidney and liver ANS: C OBJ: 2.5 3. Which of these assays is the best test to assess the bone marrow’s response to anemic stress? A. Hemoglobin value B. MCV value C. Reticulocyte count D. Hematocrit ANS: C OBJ: 2.12 4. All of the following splenic functions are related to hematopoiesis, except: A. Production of opsonizing antibodies B. Production of WBCS, if necessary C. Filtering out of old or deformed cells D. Storage of platelets and granulocytes Copyright © 2019 by F. A. Davis Company ANS: A OBJ: 2.4 5. Which of the following is a primary site for hematopoiesis in a fetus of 4 to 5 months’ gestation? A. Yolk sac B. Spleen C. Distal long bones D. Axial skeleton ANS: B OBJ: 2.2 6. A patient with the following values—RBC = 4.01  1012/L, Hgb = 12.5 g/dL, and Hct = 37.2%—will most likely have which of the following RBC indices? A. MCV = 92.8 fL, MCH = 31.2 pg, MCHC = 33.6% B. MCV = 92.8 fL, MCH = 33.6 pg, MCHC = 31.2% C. MCV = 107.8 fL, MCH = 32.1 pg, MCHC = 33.6% D. MCV = 132.2 fL, MCH = 32.1 pg, MCHC = 33.5% ANS: A OBJ: 2.9 7. The hormone responsible for red blood cell development in the bone marrow is: A. Thyroxin B. Insulin C. Leukopoietin D. Erythropoietin ANS: D OBJ: 2.1 8. Which of the following sites is the most preferable for bone marrow aspiration and biopsy in adults? A. Sternum B. Iliac crest C. Fibula Copyright © 2019 by F. A. Davis Company D. Vertebra ANS: B OBJ: 2.7 9. A patient’s hemoglobin is 12.3 g/dL. On the peripheral smear, the red cells appear normochromic and normocytic. The hematocrit value that correlates with these data is: A. 34% B. 37% C. 40% D. 43% ANS: B OBJ: 2.10 10. A Wright-stained smear of a patient’s bone marrow would effectively reveal all the following cells except: A. Iron-containing cells B. RBC precursor cells C. WBC precursor cells D. Mature WBCs ANS: A OBJ: 2.7 11. Erythropoietin is produced by the: A. Kidneys B. Liver C. Spleen D. Thymus gland ANS: A OBJ: 2.1 12. Bone marrow aspiration is usually required in conditions of: A. Anemia B. Hypoxia C. Leukemia Copyright © 2019 by F. A. Davis Company D. Hepatosplenomegaly ANS: C OBJ: 2.7 13. Opsonizing antibodies produced by the spleen serve to: A. Strip the capsule from bacterial pathogens B. Recycle erythrocyte byproducts C. Aid in extramedullary hematopoiesis D. Fight viral infection ANS: A OBJ: 2.4 14. The spleen harbors _____ of the circulatory platelet mass. A. one-quarter B. one-third C. one-half D. three-quarters ANS: B OBJ: 2.4 15. Mature red blood cells leave the bone marrow and enter the circulation via the: A. Reticuloendothelial system B. Osteoclasts C. Spleen D. Bone marrow sinuses ANS: D OBJ: 2.1 16. Which of the following is a site of extramedullary hematopoiesis in an adult? A. Spleen B. Liver C. Iliac crest D. Both A and B Copyright © 2019 by F. A. Davis Company ANS: D OBJ: 2.5 17. The ______ is one of the most stable parameters in a CBC. A. MCV B. Hct C. MCHC D. MCH ANS: A OBJ: 2.10 18. The CBC parameter that gives insight into the amount of anisocytosis present in a specimen is: A. RDW B. MCHC C. MCV D. Hgb ANS: A OBJ: 2.8 True/False 19. The CFU-GEMM is a multipotential stem cell, capable of differentiating into a lymphoid or nonlymphoid precursor committed cell. ANS: False OBJ: 2.3 20. Patients with moderate anemias (7 to 10 g/dL) may be asymptomatic. ANS: True OBJ: 2.10 Copyright © 2019 by F. A. Davis Company